THE PHARMACOGENOMICS OF EGFR-DEPENDENT NSCLC: PREDICTING AND ENHANCING RESPONSE TO TARGETED EGFR THERAPY

The introduction of tyrosine kinase inhibitors (TKI) targeting the epidermal growth factor receptor (EGFR) inhibitors to the clinic has resulted in an improvement in the treatment of non small cell lung cancer (NSCLC). However, many patients treated with EGFR TKIs do not respond to therapy. The burd...

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Bibliographic Details
Main Author: Balko, Justin M.
Format: Others
Published: UKnowledge 2009
Subjects:
Online Access:http://uknowledge.uky.edu/gradschool_diss/726
http://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1729&context=gradschool_diss