EXPERIMENTAL AND MOLECULAR DYNAMICS SIMULATION STUDIES OF PARTITIONING AND TRANSPORT ACROSS LIPID BILAYER MEMBRANES

Most drugs undergo passive transport during absorption and distribution in the body. It is desirable to predict passive permeation of future drug candidates in order to increase the productivity of the drug discovery process. Unlike drug-receptor interactions, there is no receptor map for passive pe...

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Bibliographic Details
Main Author: Tejwani, Ravindra Wadhumal
Format: Others
Published: UKnowledge 2009
Subjects:
Online Access:http://uknowledge.uky.edu/gradschool_diss/738
http://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1741&context=gradschool_diss