EXPERIMENTAL AND MOLECULAR DYNAMICS SIMULATION STUDIES OF PARTITIONING AND TRANSPORT ACROSS LIPID BILAYER MEMBRANES
Most drugs undergo passive transport during absorption and distribution in the body. It is desirable to predict passive permeation of future drug candidates in order to increase the productivity of the drug discovery process. Unlike drug-receptor interactions, there is no receptor map for passive pe...
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UKnowledge
2009
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Online Access: | http://uknowledge.uky.edu/gradschool_diss/738 http://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1741&context=gradschool_diss |