ROLE OF OXIDATIVE STRESS AND T CELL HOMING IN THE DEVELOPMENT OF MURINE SYNGENEIC GRAFT-VERSUS-HOST DISEASE

ROLE OF OXIDATIVE STRESS AND T CELL HOMING IN THE DEVELOPMENT OF MURINE SYNGENEIC GRAFT-VERSUS-HOST DISEASE

Syngeneic graft-versus-host disease (SGVHD) is induced by reconstituting lethally irradiated mice with syngeneic BM cells followed by a 21 day treatment with the immunosuppressive agent cyclosporine A (CsA). Clinical symptoms of the disease appear 2-3 weeks following cessation of CsA therapy and dis...

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Bibliographic Details
Main Author: Perez-Rodriguez, Jacqueline
Format: Others
Published: UKnowledge 2009
Subjects:
Reactive Oxygen/Nitrogen Species (ROS/RNS)|Manganese (III) mesotetrakis (4-benzoic acid) porphyrin (MnTBAP)|Cell Adhesion Molecules (CAM)|â7 integrin|T cell homing
Medical Toxicology
Online Access:http://uknowledge.uky.edu/gradschool_diss/804
http://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1807&context=gradschool_diss

Internet

http://uknowledge.uky.edu/gradschool_diss/804
http://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1807&context=gradschool_diss

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