IDENTIFICATION OF ACTIVITIES INVOLVED IN CAG/CTG REPEAT INSTABILITY

IDENTIFICATION OF ACTIVITIES INVOLVED IN CAG/CTG REPEAT INSTABILITY

CAG/CTG repeat instability is associated with at least 14 neurological disorders, including Huntington’s disease and Myotonic dystrophy type 1. In vitro and in vivo studies have showed that CAG/CTG repeats form a stable hairpin that is believed to be the intermediate for repeat expansion and contrac...

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Bibliographic Details
Main Author: Chan, Nelson Lap Shun
Format: Others
Published: UKnowledge 2011
Subjects:
CTG
Repeat Instability
Hairpin
Helicase
Polymerase
Medical Toxicology
Toxicology
Online Access:http://uknowledge.uky.edu/gradschool_diss/832
http://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1835&context=gradschool_diss

Internet

http://uknowledge.uky.edu/gradschool_diss/832
http://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1835&context=gradschool_diss

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