EFFECT OF AZITHROMYCIN ON MACROPHAGE PHENOTYPE DURING PULMONARY INFECTIONS AND CYSTIC FIBROSIS

EFFECT OF AZITHROMYCIN ON MACROPHAGE PHENOTYPE DURING PULMONARY INFECTIONS AND CYSTIC FIBROSIS

Azithromycin improves clinical outcomes in patients with cystic fibrosis (CF), specifically in patients infected with Pseudomonas aeruginosa. Azithromycin shifts macrophage programming away from a pro-inflammatory classical (M1) phenotype, and towards an anti-inflammatory alternative (M2) phenotype;...

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Bibliographic Details
Main Author: Cory, Theodore James
Format: Others
Published: UKnowledge 2011
Subjects:
Azithromycin
Macrophage phenotype
Cystic fibrosis
Pseudomonas Aeruginosa
IKKβ
Pharmacy and Pharmaceutical Sciences
Online Access:http://uknowledge.uky.edu/gradschool_diss/834
http://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1836&context=gradschool_diss

Internet

http://uknowledge.uky.edu/gradschool_diss/834
http://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1836&context=gradschool_diss

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