SOMATIC INJURY PRECEDES DISTAL ATROPHY FOLLOWING EXCITOTOXIC HIPPOCAMPAL INSULT

Excitotoxicity can lead to increases in intracellular Na+ and Ca2+ concentrations via the glutamatergic NMDA receptors, which can lead to cell death. Detailing the time-dependent degradation of neuronal components in response to excitotoxic challenge may help elucidate the sequence in which these si...

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Bibliographic Details
Main Author: Sharrett-Field, Lynda
Format: Others
Published: UKnowledge 2010
Subjects:
Online Access:http://uknowledge.uky.edu/gradschool_theses/70
http://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1077&context=gradschool_theses