SOMATIC INJURY PRECEDES DISTAL ATROPHY FOLLOWING EXCITOTOXIC HIPPOCAMPAL INSULT
Excitotoxicity can lead to increases in intracellular Na+ and Ca2+ concentrations via the glutamatergic NMDA receptors, which can lead to cell death. Detailing the time-dependent degradation of neuronal components in response to excitotoxic challenge may help elucidate the sequence in which these si...
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UKnowledge
2010
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Online Access: | http://uknowledge.uky.edu/gradschool_theses/70 http://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1077&context=gradschool_theses |