CALPAIN 5: A NON-CLASSICAL CALPAIN HIGHLY EXPRESSED IN THE CNS AND LOCALIZED TO MITOCHONDRIA AND NUCLEAR PML BODIES
Calpain 5 (CAPN5) is a non-classical member of the calpain family. It lacks the EF-hand motif characteristic of the classical calpains, calpain 1 and 2, but retains catalytic and Ca2+ binding non EF domains. Tra-3, an ortholog of CAPN5, is involved in necrotic cell death in C.elegans; although speci...
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| Format: | Others |
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UKnowledge
2014
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| Online Access: | http://uknowledge.uky.edu/neurobio_etds/9 http://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1007&context=neurobio_etds |