BEYOND PEROXISOME: ABCD2 MODIFIES PPARα SIGNALING AND IDENTIFIES A SUBCLASS OF PEROXISOMES IN MOUSE ADIPOSE TISSUE
ABCD2 (D2) has been proposed as a peroxisomal long-chain acyl-CoA transporter that is essential for very long chain fatty acid metabolism. In the livers of mice, D2 is highly induced by fenofibrate, a PPARα ligand that has been widely used as a lipid lowering agent in the treatment of hypertriglycer...
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| Format: | Others |
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UKnowledge
2014
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| Online Access: | http://uknowledge.uky.edu/pharmacy_etds/41 http://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1038&context=pharmacy_etds |