Chemoenzymatic Studies to Enhance the Chemical Space of Natural Products

Chemoenzymatic Studies to Enhance the Chemical Space of Natural Products

Natural products provide some of the most potent anticancer agents and offer a template for new drug design or improvement with the advantage of an enormous chemical space. The overall goal of this thesis research is to enhance the chemical space of two natural products in order to generate novel dr...

Full description

Bibliographic Details
Main Author: Chen, Jhong-Min
Format: Others
Published: UKnowledge 2015
Subjects:
gilvocarcin V
polycarcin V
mithramycin
MtmC
chemical space
Bacteriology
Biochemistry
Carbohydrates
Enzymes and Coenzymes
Heterocyclic Compounds
Medicinal and Pharmaceutical Chemistry
Medicinal Chemistry and Pharmaceutics
Molecular Biology
Natural Products Chemistry and Pharmacognosy
Neoplasms
Organic Chemicals
Organic Chemistry
Pharmaceutics and Drug Design
Structural Biology
Online Access:http://uknowledge.uky.edu/pharmacy_etds/48
http://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1052&context=pharmacy_etds

Internet

http://uknowledge.uky.edu/pharmacy_etds/48
http://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1052&context=pharmacy_etds

Similar Items