THE DEVELOPMENT OF NOVEL NON-PEPTIDE PROTEASOME INHIBITORS FOR THE TREATMENT OF SOLID TUMORS

THE DEVELOPMENT OF NOVEL NON-PEPTIDE PROTEASOME INHIBITORS FOR THE TREATMENT OF SOLID TUMORS

The proteasome is a large protein complex which is responsible for the majority of protein degradation in eukaryotes. Following FDA approval of the first proteasome inhibitor bortezomib for the treatment of multiple myeloma (MM) in 2003, there has been an increasing awareness of the significant ther...

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Bibliographic Details
Main Author: Miller, Zachary C.
Format: Others
Published: UKnowledge 2018
Subjects:
Proteasome
Screening
Non-Peptide
Cancer
Medicinal Chemistry
Drug Discovery
Medicinal and Pharmaceutical Chemistry
Medicinal Chemistry and Pharmaceutics
Pharmacology
Online Access:https://uknowledge.uky.edu/pharmacy_etds/87
https://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1091&context=pharmacy_etds

Internet

https://uknowledge.uky.edu/pharmacy_etds/87
https://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1091&context=pharmacy_etds

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