Pharmacokinetic and Pharmacodynamic Evaluation of Cocaine Hydrolases for the Treatment of Cocaine Overdose and Cocaine Addiction Using Rodent Models

Overdose and addiction are two medical complications of cocaine abuse. To date, there is no FDA approved pharmacotherapy specific for cocaine abuse. Cocaine hydrolases (CocHs) have been extensively investigated for its potential in anti-cocaine therapy. Previous studies have demonstrated that CocHs...

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Bibliographic Details
Main Author: Zheng, Xirong
Format: Others
Published: UKnowledge 2019
Subjects:
Online Access:https://uknowledge.uky.edu/pharmacy_etds/102
https://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1107&context=pharmacy_etds