Pharmacokinetic and Pharmacodynamic Evaluation of Cocaine Hydrolases for the Treatment of Cocaine Overdose and Cocaine Addiction Using Rodent Models
Overdose and addiction are two medical complications of cocaine abuse. To date, there is no FDA approved pharmacotherapy specific for cocaine abuse. Cocaine hydrolases (CocHs) have been extensively investigated for its potential in anti-cocaine therapy. Previous studies have demonstrated that CocHs...
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UKnowledge
2019
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Online Access: | https://uknowledge.uky.edu/pharmacy_etds/102 https://uknowledge.uky.edu/cgi/viewcontent.cgi?article=1107&context=pharmacy_etds |