Insight into the activation mechanism of Toll-like receptor 4 by diC14-amidine

Insight into the activation mechanism of Toll-like receptor 4 by diC14-amidine

SUMMARY:<p>The bacterial lipopolysaccharide (LPS)-sensing machinery with the innate immune system receptor Toll-like receptor 4 (TLR4) at its centre has been the subject of extensive research but while TLR4 and myeloid differentiation factor 2 (MD2) were both shown to be essential, the role of...

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Bibliographic Details
Main Author: Schmidt, Boris
Other Authors: Ruysschaert, Jean Marie
Format: Doctoral Thesis
Language:fr
Published: Universite Libre de Bruxelles 2014
Subjects:
Chimie
Sciences exactes et naturelles
Endotoxins
Natural immunity
Amidines
Endocytosis
Endotoxines
Immunité naturelle
Endocytose
lipopolysaccharides
cationic lipid
diC14-amidine
lipopolysaccharide
endocytose
endocytosis
cluster of differentiation 14
LPS
Toll-like receptor 4
TLR-4
TLR4
MyD88
lipide cationique
TRIF
CD-14
CD14
immunité innée
innate immunity
Online Access:http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/209250

Internet

http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/209250

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