Unraveling Alzheimer's disease: insight into the influence of apolipoprotein E isoforms on Abeta aggregation

Nowadays, the emerging role of amyloid-β peptide (Aβ) oligomers in Alzheimer’s disease (AD) is widely accepted, putting aside the old idea that fibrils are the primary entities responsible for the onset of the disease. Recent studies indeed show that the level of soluble Aβ oligomeric forms better c...

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Bibliographic Details
Main Author: Cerf, Emilie
Other Authors: Raussens, Vincent
Format: Doctoral Thesis
Language:fr
Published: Universite Libre de Bruxelles 2011
Subjects:
Online Access:http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/209880