Unraveling Alzheimer's disease: insight into the influence of apolipoprotein E isoforms on Abeta aggregation
Nowadays, the emerging role of amyloid-β peptide (Aβ) oligomers in Alzheimer’s disease (AD) is widely accepted, putting aside the old idea that fibrils are the primary entities responsible for the onset of the disease. Recent studies indeed show that the level of soluble Aβ oligomeric forms better c...
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Format: | Doctoral Thesis |
Language: | fr |
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Universite Libre de Bruxelles
2011
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Online Access: | http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/209880 |