Cyclic AMP-dependent signal transduction leading to mitogenesis in thyroid: implication of the mammalian target of rapamycin
Abnormal thyroid cell proliferation causes human diseases, such as goiter, thyroid adenoma or carcinoma and primary hypothyroidism resulting from hypoplasia. Thyrotropin (TSH), mainly acting through cAMP and cAMP-dependent protein kinases (PKA), is considered the main regulator of thyrocyte prolifer...
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| Format: | Doctoral Thesis |
| Language: | en |
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Universite Libre de Bruxelles
2010
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| Online Access: | http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/210093 |