Study of the scaffold properties of the phosphatidylinositol 5-phosphatase SHIP2 by characterization of two binding partners JIP1 and Intersectin1

Study of the scaffold properties of the phosphatidylinositol 5-phosphatase SHIP2 by characterization of two binding partners JIP1 and Intersectin1

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SH2-containing inositol polyphosphate 5-phosphatases, SHIP2, has been established as a regulator of the insulin cascade, of cell adhesion and spreading, actin structures, remodelling and cytoskeletal organization. However, the molecular mechanisms underlying these processes still needed additional i...

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Bibliographic Details
Main Author: Xie, Jingwei
Other Authors: Pirson, Isabelle
Format: Doctoral Thesis
Language:en
Published: Universite Libre de Bruxelles 2009
Subjects:
Disciplines biomédicales diverses
Médecine pathologie humaine
Phosphoinositides
Cellular signal transduction
Endocytosis
Phospho-inositides
Transduction du signal cellulaire
Endocytose
Signal transduction
phosphoinositides
endocytosis
Online Access:http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/210299

Internet

http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/210299

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