The Complex Role of Sequence and Structure in the Stability and Function of the TIM Barrel Proteins
Sequence divergence of orthologous proteins enables adaptation to a plethora of environmental stresses and promotes evolution of novel functions. As one of the most common motifs in biology capable of diverse enzymatic functions, the TIM barrel represents an ideal model system for mapping the phenot...
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| Format: | Others |
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eScholarship@UMMS
2017
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| Online Access: | https://escholarship.umassmed.edu/gsbs_diss/934 https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=1940&context=gsbs_diss |