SERINC5: Its Sensitivity to Nef and Restriction of HIV-1

The accessory protein Nef of human immunodeficiency virus type 1 (HIV-1) has long been known to enhance the infectivity of HIV-1 progeny virions. The multipass transmembrane proteins serine incorporator 3 (SERINC3) and SERINC5 were recently identified as novel antiviral proteins that restrict HIV-1...

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Bibliographic Details
Main Author: Dai, Weiwei
Format: Others
Published: eScholarship@UMMS 2018
Subjects:
Nef
Online Access:https://escholarship.umassmed.edu/gsbs_diss/984
https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=1989&context=gsbs_diss