Characterization of the caspase-3 cleavage motif of the Salmonella Typhimurium effector protein SifA and its role in pathogenesis

Salmonella enterica serovar Typhimurium (S. Typhimurium) is a Gram-negative facultative anaerobe that induces severe inflammation resulting in gastroenteritis. In the case of S. Typhimurium infection, induction of an inflammatory response has been linked to its primary virulence mechanism, the type...

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Bibliographic Details
Main Author: Patel, Samir
Format: Others
Published: eScholarship@UMMS 2018
Subjects:
Online Access:https://escholarship.umassmed.edu/gsbs_diss/1002
https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=2010&context=gsbs_diss