The Role of Interferon Gamma in Melanocyte Clearance During Vitiligo

The Role of Interferon Gamma in Melanocyte Clearance During Vitiligo

Vitiligo is an autoimmune disease in which CD8+ T cells selectively destroy melanocytes, leading to a patchy, disfiguring depigmentation of the skin. Our group and others have highlighted the central role of IFN-γ-dependent chemokines in the progression of disease; however, IFN-γ is also reported to...

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Bibliographic Details
Main Author: Strassner, James P.
Format: Others
Published: eScholarship@UMMS 2019
Subjects:
Vitiligo
autoimmunity
biomarker
single-cell RNA-sequencing
T cell
melanocyte
T-cell effector functions
Bioinformatics
Dermatology
Immune System Diseases
Immunity
Skin and Connective Tissue Diseases
Translational Medical Research
Online Access:https://escholarship.umassmed.edu/gsbs_diss/1023
https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=2034&context=gsbs_diss

Internet

https://escholarship.umassmed.edu/gsbs_diss/1023
https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=2034&context=gsbs_diss

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