TREX Function in piRNA Biogenesis and Transposon Silencing

The Piwi interacting RNA pathway (piRNA) transcriptionally and post-transcriptionally silences transposons in the germline to maintain host genome integrity and faithful transmission of the genetic materials. In Drosophilaovaries, maternally loaded piRNAs kick-start piRNA biogenesis and convert prec...

Full description

Bibliographic Details
Main Author: Zhang, Gen
Format: Others
Published: eScholarship@UMMS 2019
Subjects:
THO
Online Access:https://escholarship.umassmed.edu/gsbs_diss/1056
https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=2065&context=gsbs_diss