Measuring Stability of 3D Chromatin Conformations and Identifying Neuron Specific Chromatin Loops Associated with Schizophrenia Risk

The 23 pairs of chromosomes comprising the human genome are intricately folded within the nucleus of each cell in a manner that promotes efficient gene regulation and cell function. Consequently, active gene rich regions are compartmentally segregated from inactive gene poor regions of the genome. T...

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Bibliographic Details
Main Author: Borrman, Tyler M.
Format: Others
Published: eScholarship@UMMS 2020
Subjects:
Online Access:https://escholarship.umassmed.edu/gsbs_diss/1111
https://escholarship.umassmed.edu/cgi/viewcontent.cgi?article=2121&context=gsbs_diss