Biotransformation of fusidic acid and its related derivatives by Streptomyces lividans
As shown in previous studies Streptomyces lividans enzymatically inactivates fusidic acid by specific esterase FusH giving rise to the 16ß-OH derivative, which sponaneously converts to the lactone.in this work it was shown that S. lividans further modifies fusidic acid and both derivatives, which re...
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Format: | Doctoral Thesis |
Language: | English |
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2005
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Online Access: | https://repositorium.ub.uni-osnabrueck.de/handle/urn:nbn:de:gbv:700-2005033013 |