Site-specific modification strategies for unravelling energetics and dynamics of type I interferon receptor complex
Signal propagation across the membrane by cytokine receptor signalling involves a complex interplay of receptor-ligand interactions, allostery and conformational changes. Type I interferons (IFNs) exert their biological activities through binding to a shared receptor consisting of the type II cytoki...
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| Format: | Doctoral Thesis |
| Language: | English |
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2013
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| Online Access: | https://repositorium.ub.uni-osnabrueck.de/handle/urn:nbn:de:gbv:700-2013041910791 |