Toxicity and biotransformation of 1,1,1,3,3-Pentafluoropropane, 3,3,3-Trifluoropropionic acid and 1,1,1,3-Tetrachloropropane
The biotransformation of 1,1,1,3,3-pentafluoropropane was investigated in rats and in in vitro systems. First, the metabolites were identified in vivo using GC/MS and 19F NMR analysis. The main metabolite was identified as trifluoroacetic acid, the minor metabolite as 3,3,3-trifluoropropionic acid a...
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Format: | Doctoral Thesis |
Language: | English |
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2005
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Online Access: | https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/1340 http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-15731 https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-15731 https://opus.bibliothek.uni-wuerzburg.de/files/1340/TanjaBayer_2005_DISS.pdf |