Characterization of Novel Mutations in Receptor-Tyrosine Kinases in Multiple Myeloma

Multiple myeloma (MM) is a disease of terminally differentiated B-cells which accumulate in the bone marrow leading to bone lesions, hematopoietic insufficiency and hypercalcemia. Genetically, MM is characterized by a great heterogeneity. A recent next-generation sequencing approach resulted in the...

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Bibliographic Details
Main Author: Keppler, Sarah
Format: Doctoral Thesis
Language:English
Published: 2020
Subjects:
Online Access:https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/15572
http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-155720
https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-155720
https://doi.org/10.25972/OPUS-15572
https://opus.bibliothek.uni-wuerzburg.de/files/15572/Keppler_Sarah_Dissertation.pdf