A mathematical optimal control based approach to pharmacological modulation with regulatory networks and external stimuli

In this work models for molecular networks consisting of ordinary differential equations are extended by terms that include the interaction of the corresponding molecular network with the environment that the molecular network is embedded in. These terms model the effects of the external stimuli on...

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Bibliographic Details
Main Author: Breitenbach, Tim
Format: Doctoral Thesis
Language:English
Published: 2019
Subjects:
Online Access:https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/17436
http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-174368
https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-174368
https://opus.bibliothek.uni-wuerzburg.de/files/17436/Circadian_clock.zip
https://opus.bibliothek.uni-wuerzburg.de/files/17436/Small_T_cell_network.zip
https://opus.bibliothek.uni-wuerzburg.de/files/17436/Myocardiocyte.zip
https://opus.bibliothek.uni-wuerzburg.de/files/17436/Platelet.zip
https://opus.bibliothek.uni-wuerzburg.de/files/17436/T_cell.zip
https://opus.bibliothek.uni-wuerzburg.de/files/17436/Breitenbach_Tim_Dissertation.pdf