Role and regulation of the p53-homolog p73 in the transformation of normal human fibroblasts
The prototyical tumor suppressor p53 is able to arrest cells after DNA damage or as a response to oncogene expression. The transactivation-competent (TA) isoforms of the more recently discovered p53 family member p73 also prevent tumors, but the underlying mechanisms are less well understood. The wo...
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Format: | Doctoral Thesis |
Language: | English |
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2008
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Online Access: | https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/2305 http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-26877 https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-26877 https://opus.bibliothek.uni-wuerzburg.de/files/2305/LarsHofmannDiss.pdf |