Role and regulation of the p53-homolog p73 in the transformation of normal human fibroblasts

The prototyical tumor suppressor p53 is able to arrest cells after DNA damage or as a response to oncogene expression. The transactivation-competent (TA) isoforms of the more recently discovered p53 family member p73 also prevent tumors, but the underlying mechanisms are less well understood. The wo...

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Bibliographic Details
Main Author: Hofmann, Lars
Format: Doctoral Thesis
Language:English
Published: 2008
Subjects:
Online Access:https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/2305
http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-26877
https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-26877
https://opus.bibliothek.uni-wuerzburg.de/files/2305/LarsHofmannDiss.pdf