Aurora-A prevents transcription-replication conflicts in MYCN-amplified neuroblastoma

Neuroblastoma is the most abundant, solid, extracranial tumor in early childhood and the leading cause of cancer-related childhood deaths worldwide. Patients with high-risk neuroblastoma often show MYCN-amplification and elevated levels of Aurora-A. They have a low overall survival and despite multi...

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Bibliographic Details
Main Author: Röschert, Isabelle
Format: Doctoral Thesis
Language:English
Published: 2021
Subjects:
Online Access:https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/24303
http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-243037
https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-243037
https://doi.org/10.25972/OPUS-24303
https://opus.bibliothek.uni-wuerzburg.de/files/24303/Roeschert_Isabelle_Aurora-A.pdf