Molecular Mechanisms of MYC’s impact on Transcription Elongation

Expression of the MYC oncoprotein, which binds the DNA at promoters of most transcribed genes, is controlled by growth factors in non-tumor cells, thus stimulating cell growth and proliferation. Here in this thesis, it is shown that MYC interacts with SPT5, a subunit of the RNA polymerase II (Pol I...

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Bibliographic Details
Main Author: Baluapuri, Apoorva
Format: Doctoral Thesis
Language:English
Published: 2021
Subjects:
Online Access:https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/24380
http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-243806
https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-243806
https://doi.org/10.25972/OPUS-24380
https://opus.bibliothek.uni-wuerzburg.de/files/24380/Baluapuri_Apoorva_Thesis.pdf