Structural and Functional Analysis of Chordin-like 2/BMP-2 Interaction
We have established the novel interaction between mCHL2, Tsg and BMP-2 for the first time. Tsg binds to VWC1 and VWC3 of mCHL2 in a cooperative waz and plazs a role in strengthening the binding affinity. Furthermore, Tsg/mCHL2/BMP-2 termary complex and Tsg/mCHL2 binary complex have been isolated by...
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| Format: | Doctoral Thesis |
| Language: | English |
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2008
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| Online Access: | https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/2497 http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-29120 https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-29120 https://opus.bibliothek.uni-wuerzburg.de/files/2497/thesis_huangyi.pdf |