Regulation and functional consequences of MCP-1 expression in a model of Charcot-Marie-Tooth 1B disease
Charcot-Marie-Tooth 1B (CMT1B) is a progressive inherited demyelinating disease of human peripheral nervous system leading to sensory and/or motor function disability and is caused by mutations in the P0 gene. Mice heterozygously deficient for P0 (P0+/-) are an adequate model of this human disorder...
Main Author: | |
---|---|
Format: | Doctoral Thesis |
Language: | English |
Published: |
2008
|
Subjects: | |
Online Access: | https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/2525 http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-29189 https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-29189 https://opus.bibliothek.uni-wuerzburg.de/files/2525/FischerStefanDiss.pdf |