Evaluation of 1H-NMR and GC/MS-based metabonomics for the assessment of liver and kidney toxicity

For the assessment of metabonomics techniques for the early, non-invasive detection of toxicity, the nephrotoxins gentamicin (s.c. administration of 0, 60 and 120 mg/kg bw 2x daily for 8 days), ochratoxin A (p.o. administration of 0, 21, 70 and 210 µg/kg bw 5 days/week for 90 days) and aristolochic...

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Bibliographic Details
Main Author: Sieber, Maximilian
Format: Doctoral Thesis
Language:English
Published: 2009
Subjects:
Online Access:https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/3505
http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-43052
https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-43052
https://opus.bibliothek.uni-wuerzburg.de/files/3505/Dissertation_Sieber.pdf