Analysis of the factor XII-driven contact system activation in vivo
Platelets play a central role in thrombosis, hemostasis, and inflammation. Here, we show that activated platelets release inorganic polyphosphate (polyP), a polymer of 60- 100 phosphate residues that directly bound to and activated the plasma protease factor XII. PolyP-driven factor XII-activation t...
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| Format: | Doctoral Thesis |
| Language: | English |
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2010
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| Online Access: | https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/3725 http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-46071 https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-46071 https://opus.bibliothek.uni-wuerzburg.de/files/3725/PhD_Mueller.pdf |