Aspects of the mode of action of bispecific T cell engager (BiTE) antibodies

Bispecific T cell engager (BiTE) display a novel design among the class of bispecific antibodies and hold great promise to fight diverse cancers. BiTE molecules consist of two different binding entities derived from two human IgG antibodies connected by a short peptide linker. Their binding arms are...

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Bibliographic Details
Main Author: Hauff, Cornelia
Format: Doctoral Thesis
Language:English
Published: 2009
Subjects:
Online Access:https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/3969
http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-48369
https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-48369
https://opus.bibliothek.uni-wuerzburg.de/files/3969/Hauffdiss.pdf