Characterization of allosteric mechanisms on the M2 and M4 mACh receptor using the FRET-technique
Allosteric modulators have been proposed as promising new compounds to modify protein function. Allosteric binding sites have been discovered for several G-protein-coupled receptors, including M1-5 muscarinic receptors. Since these receptors play a pivotal role in the regulation of a plethora of org...
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| Format: | Doctoral Thesis |
| Language: | English |
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2010
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| Online Access: | https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/4101 http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-49237 https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-49237 https://opus.bibliothek.uni-wuerzburg.de/files/4101/Dissertation_Monika_Maier_Peuschel_neu.pdf |