Characterisation and regulation of the Egfr/Egfr ligand system in fish models for melanoma
Fish of the genus Xiphophorus belong to the oldest animal models in cancer research. The oncogene responsible for the generation of spontaneous aggressive melanoma encodes for a mutated epidermal growth factor receptor (Egfr) and is called xmrk for Xiphophorus melanoma receptor kinase. Xmrk constitu...
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| Format: | Doctoral Thesis |
| Language: | English |
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2010
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| Online Access: | https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/4253 http://nbn-resolving.de/urn:nbn:de:bvb:20-opus-51369 https://nbn-resolving.org/urn:nbn:de:bvb:20-opus-51369 https://opus.bibliothek.uni-wuerzburg.de/files/4253/Thesis_J_Laisney_PDF.pdf |