ATG based combination therapy - a novel clinically relevant approach to promote regulation and induce long-term allograft survival
Regulatory T cells (Treg) actively regulate alloimmune responses and promote transplantation tolerance. Polyclonal anti-thymocyte globulin (ATG), a widely used induction therapy in clinical organ transplantation, depletes peripheral T cells. However, resistance to tolerance induction is seen with ce...
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Format: | Doctoral Thesis |
Language: | en |
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Alma Mater Studiorum - Università di Bologna
2009
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Online Access: | http://amsdottorato.unibo.it/2167/ |