Reconstruction and analysis of the NF-kB pathway interactome: a systems biology approach
Background. One of the phenomena observed in human aging is the progressive increase of a systemic inflammatory state, a condition referred to as “inflammaging”, negatively correlated with longevity. A prominent mediator of inflammation is the transcription factor NF-kB, that acts as key transcripti...
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Format: | Doctoral Thesis |
Language: | en |
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Alma Mater Studiorum - Università di Bologna
2010
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Online Access: | http://amsdottorato.unibo.it/2317/ |