Effetti clinici e biologici della terapia epigenetica nelle sindromi mielodisplastiche a basso rischio
Background: Nucleoside 5-Azacitidine (5-Aza) in high risk MDS patients (pts) at a dose of 75mg/mq/day subcutaneously for 7 days, every 28 days, induces high hematologic response rates (hematologic improvement (HI) 50-60%, complete remission (CR) 10-30%) and prolongation of survival (at 2 years 50,8...
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Format: | Doctoral Thesis |
Language: | it |
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Alma Mater Studiorum - Università di Bologna
2010
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Online Access: | http://amsdottorato.unibo.it/2419/ |