Effect of loss of CDKL5 on brain development in a new Cdkl5 knockout mouse model

Rett's Syndrome (RTT) is a severe neurodevelopmental disorder, characterized by cognitive disability that appears in the first months/years of life. Recently, mutations in the X-linked cyclin-dependent kinase-like 5 (CDKL5) gene have been detected in RTT patients characterized by early-onset se...

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Bibliographic Details
Main Author: Fuchs, Claudia <1983>
Other Authors: Ciani, Elisabetta
Format: Doctoral Thesis
Language:en
Published: Alma Mater Studiorum - Università di Bologna 2014
Subjects:
Online Access:http://amsdottorato.unibo.it/6190/