Cancer and aging: a multidisciplinary medicinal chemistry approach on relevant biological targets such as proteasome, sirtuins and interleukin 6
It is well known that ageing and cancer have common origins due to internal and environmental stress and share some common hallmarks such as genomic instability, epigenetic alteration, aberrant telomeres, inflammation and immune injury. Moreover, ageing is involved in a number of events responsible...
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Format: | Doctoral Thesis |
Language: | en |
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Alma Mater Studiorum - Università di Bologna
2015
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Online Access: | http://amsdottorato.unibo.it/6801/ |