Analysis of the role of arginine methylation in the pathogenesis of Huntington’s disease

Analysis of the role of arginine methylation in the pathogenesis of Huntington’s disease

Huntington's disease (HD) is a fatal neurodegenerative disorder characterized by progressive loss of striatal and cortical neurons. HD is caused by an abnormal polyglutamine (polyQ) expansion in Huntingtin protein (HTT). HTT controls vesicular trafficking along axons in neurons through interact...

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Bibliographic Details
Main Author: Migazzi, Alice
Other Authors: Basso, Manuela
Format: Doctoral Thesis
Language:English
Published: Università degli studi di Trento 2019
Subjects:
Huntingtin Arginine Methylation Axonal transport Huntington's Disease
Settore BIO/13 - Biologia Applicata
Online Access:http://hdl.handle.net/11572/242962

Internet

http://hdl.handle.net/11572/242962

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