Truncated BRPF1 cooperates with Smoothened to promote adult Shh medulloblastoma
Tumors are composed of proliferating cells that invade healthy tissue and grow over time. Even though it is still unclear, it is a common opinion that the cells of origin should possess a proliferative capacity (Blanpain, 2013; Visvader, 2011). Particularly for brain cancers, the transition of neura...
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Format: | Doctoral Thesis |
Language: | English |
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Università degli studi di Trento
2020
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Online Access: | http://hdl.handle.net/11572/262675 |