Truncated BRPF1 cooperates with Smoothened to promote adult Shh medulloblastoma

Tumors are composed of proliferating cells that invade healthy tissue and grow over time. Even though it is still unclear, it is a common opinion that the cells of origin should possess a proliferative capacity (Blanpain, 2013; Visvader, 2011). Particularly for brain cancers, the transition of neura...

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Bibliographic Details
Main Author: Aiello, Giuseppe
Other Authors: Tiberi, Luca
Format: Doctoral Thesis
Language:English
Published: Università degli studi di Trento 2020
Subjects:
Online Access:http://hdl.handle.net/11572/262675