Effects of Pharmacological De-prenylation of Rhes on Motor Behavior in a Beta-Nitropropionic Acid Animal Model of Huntington's Disease
Huntington’s disease (HD) is a heritable, neurodegenerative disorder characterized by motor, cognitive, and psychiatric disturbances. The progressive disease is caused by an unstable CAG expansion within the gene that normally encodes for the huntingtin protein (Htt). The expanded mutant form of Htt...
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Format: | Others |
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ScholarWorks@UNO
2015
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Online Access: | http://scholarworks.uno.edu/td/2115 http://scholarworks.uno.edu/cgi/viewcontent.cgi?article=3201&context=td |