Effects of Pharmacological De-prenylation of Rhes on Motor Behavior in a Beta-Nitropropionic Acid Animal Model of Huntington's Disease

Effects of Pharmacological De-prenylation of Rhes on Motor Behavior in a Beta-Nitropropionic Acid Animal Model of Huntington's Disease

Huntington’s disease (HD) is a heritable, neurodegenerative disorder characterized by motor, cognitive, and psychiatric disturbances. The progressive disease is caused by an unstable CAG expansion within the gene that normally encodes for the huntingtin protein (Htt). The expanded mutant form of Htt...

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Bibliographic Details
Main Author: Whitmarsh, Ashley
Format: Others
Published: ScholarWorks@UNO 2015
Subjects:
Huntington’s disease
motor deficits
Rhes
statin
bisphosphonate
prenylation
Biological Psychology
Online Access:http://scholarworks.uno.edu/td/2115
http://scholarworks.uno.edu/cgi/viewcontent.cgi?article=3201&context=td

Internet

http://scholarworks.uno.edu/td/2115
http://scholarworks.uno.edu/cgi/viewcontent.cgi?article=3201&context=td

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