Synthesis and Screening of a Combinatorial Peptide Library for Ligands to Target Transferrin: Miniaturizing the Library

Combinatorial libraries are used in the search for ligands that bind to target proteins. Fmoc solid-phase peptide synthesis is routinely used to generate such libraries. Microwave-assisted peptide synthesis was employed here to decrease reaction times by 80-90%. Two One-Bead-One-Compound combinatori...

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Bibliographic Details
Main Author: Brown, Jennifer Marie
Other Authors: Petros, Robby A.
Format: Others
Language:English
Published: University of North Texas 2010
Subjects:
Online Access:https://digital.library.unt.edu/ark:/67531/metadc30440/