Effects of Exogenous Steroids on the Adrenal Plasma Membrane Alteration of Steroidogenesis and Cell Morphology

Using cultured Y-1 mouse adrenal tumor cells which produce the steroid 20(-hydroxypregn-4-en-3-one (20-DHP), it was found that 10-5 M corticosterone and deoxycorticosterone increased basal and inhibited ACTH-induced 20-DHP production. The steroid effects were concentration-dependent, reversible, and...

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Bibliographic Details
Main Author: Mattson, Mark Paul
Other Authors: Mrotek, James J.
Format: Others
Language:English
Published: North Texas State University 1982
Subjects:
Online Access:https://digital.library.unt.edu/ark:/67531/metadc504128/