Investigating Pathogenic Mechanisms of the Helicobacter pylori Virulence Factor CagA Using Transgenic Expression in Drosophila melanogaster

99 pages === Upon colonization of the human stomach, Helicobacter pylori establishes intimate interactions with the gastric epithelium, resulting in pathogenic host responses that can lead to gastric cancer. An important component of this interaction is translocation of the CagA effector protein int...

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Bibliographic Details
Main Author: Wandler, Anica M.
Language:en_US
Published: University of Oregon 2012
Online Access:http://hdl.handle.net/1794/12477