Platinum-seq: High-throughput mapping of small-molecule platinum adducts on cellular RNA

Methods to map small-molecule interactions with cellular RNAs are important for understanding endogenous activation, such as in riboswitches, as well as the potential for exogenous compounds to target RNA. Cisplatin is one of the most widely used of the platinum anticancer drugs that are prescribed...

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Bibliographic Details
Main Author: Plakos, Kory
Other Authors: Hawley, Diane
Language:en_US
Published: University of Oregon 2017
Subjects:
RNA
Online Access:http://hdl.handle.net/1794/22269