Deciphering the "Polarity Code": the Mechanism of Par Complex Substrate Polarization

Animal cells, as distinct as epithelia and migratory cells, have cell polarity that is defined by a common set of molecules. The Par complex polarizes the cortex of animal cells through the activity of atypical protein kinase C (aPKC). In this work, I aimed to determine the mechanism of aPKC substra...

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Bibliographic Details
Main Author: Bailey, Matthew
Other Authors: Prehoda, Kenneth
Language:en_US
Published: University of Oregon 2017
Subjects:
Online Access:http://hdl.handle.net/1794/22782