Quantitative Subcellular Analysis of the Effects of the Enigmatic Protein PCSK9
PCSK9 is the third gene implicated in autosomal dominant hypercholesterolemia, due to its role in promoting the degradation of the low density lipoprotein receptor (LDLR). Little is known regarding the mechanism by which it promotes the degradation of LDLR, nor the effects PCSK9 has on other cellul...
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Université d'Ottawa / University of Ottawa
2011
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| Online Access: | http://hdl.handle.net/10393/20133 http://dx.doi.org/10.20381/ruor-4709 |